2-amino-2-[2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl]propane-1,3-diol hydrochloride
KRP-203
CAS: 509088-69-1
Molecular Formula: C24H27Cl2NO3S
2-amino-2-[2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl]propane-1,3-diol hydrochloride - Names and Identifiers
2-amino-2-[2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl]propane-1,3-diol hydrochloride - Physico-chemical Properties
| Molecular Formula | C24H27Cl2NO3S |
| Molar Mass | 480.45 |
| Melting Point | 199-200 ºC (DEC.) |
| Boling Point | 657.1°C at 760 mmHg |
| Flash Point | 351.2°C |
| Solubility | DMSO, Methanol |
| Vapor Presure | 3.67E-18mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | Refrigerator |
2-amino-2-[2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl]propane-1,3-diol hydrochloride - Introduction
KRP-203(KRP-203) is a compound with the chemical name (S)-3-((S)-2-(m-(p-chlorophenyl) pentafluoromethylpyridinyl) propionic acid)-4-(3-methoxyphenyl)-2-hydroxy-2-methylbutanoic acid.
The main use of the KRP-203 is as an immunosuppressant, especially for the prevention and treatment of transplant rejection after organ transplantation. It inhibits the function of the immune system and reduces the activity and lethality of immune cells, thereby reducing the rejection after organ transplantation.
The method for preparing KRP-203 is to first synthesize (S)-3-(2-(p-chlorophenyl) pentafluoromethylphenyl) propionyl chloride, and then react with 2-methoxyphenol to generate the target product.
In terms of safety, KRP-203 is a toxic compound and requires attention to safe operation. Be careful to avoid contact with skin and eyes, and seek medical help immediately if ingested or inhaled. When using KRP-203, follow appropriate precautions, such as wearing protective gloves and eye protection.
The main use of the KRP-203 is as an immunosuppressant, especially for the prevention and treatment of transplant rejection after organ transplantation. It inhibits the function of the immune system and reduces the activity and lethality of immune cells, thereby reducing the rejection after organ transplantation.
The method for preparing KRP-203 is to first synthesize (S)-3-(2-(p-chlorophenyl) pentafluoromethylphenyl) propionyl chloride, and then react with 2-methoxyphenol to generate the target product.
In terms of safety, KRP-203 is a toxic compound and requires attention to safe operation. Be careful to avoid contact with skin and eyes, and seek medical help immediately if ingested or inhaled. When using KRP-203, follow appropriate precautions, such as wearing protective gloves and eye protection.
Last Update：2024-04-09 19:05:50
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